What is a Sensitization Test?

Sensitization test is the tissue damage or physiological dysfunction that occurs when a sensitized body contacts the same antigen or hapten again. The following three test methods are commonly used in Medical Device Sensitization Test:

• Guinea pig maximum dose method (GPMT)
• Closed patch method (Buehler test)
• Local lymph node test method (LLNA)

Among them, the guinea pig maximum dose method (GPMT) and the closed patch method (Buehler test) are the two most commonly used methods with the highest usage rate in biosafety evaluation.