https://medixway.com/vicodin-vs-tramadol/ 

Vicodin and Tramadol are both prescription medications used for pain relief, but they differ in potency, mechanism, and effectiveness. Vicodin combines hydrocodone, an opioid, with acetaminophen and is generally stronger, making it suitable for moderate to severe pain. It works by binding to opioid receptors in the brain and spinal cord, altering pain perception.Tramadol, a weaker opioid, also affects serotonin and norepinephrine levels, making it effective for moderate pain but less potent than Vicodin. While Tramadol may have a lower risk of dependence, Vicodin typically provides stronger and faster relief. Choosing between them depends on pain severity, patient health, and risk factors, and should always be guided by a healthcare provider.