https://medixway.com/nucynta-vs-percocet/ 

Nucynta (tapentadol) and Percocet (oxycodone/acetaminophen) are both prescription pain medications, but they differ in composition and how they relieve pain. Nucynta works by targeting both opioid and norepinephrine pathways, offering strong pain relief with a potentially lower risk of side effects like nausea or constipation. Percocet combines oxycodone, an opioid, with acetaminophen to enhance pain control, making it effective for moderate to severe pain. However, because of the acetaminophen content, long-term use may increase the risk of liver damage. Both medications should be used strictly under medical supervision to avoid dependence or misuse. Your doctor will determine whether Nucynta or Percocet is better suited for your pain condition based on your medical history and treatment needs.