https://medixway.com/oxycodone-and-gabapentin/ 

Taking Oxycodone and Gabapentin together for pain relief may be prescribed in certain cases, as they work differently in the body to manage pain. Oxycodone is an opioid that targets pain receptors in the brain and spinal cord, while Gabapentin is an anticonvulsant that calms nerve activity often associated with neuropathic pain. When combined under medical supervision, they may provide stronger relief for complex or chronic pain conditions. However, using both drugs increases the risk of side effects such as dizziness, drowsiness, confusion, and slowed breathing. Patients should never mix these medications without a doctor’s approval and must follow prescribed doses closely. Regular monitoring helps ensure safety and effectiveness while reducing risks of dependency or dangerous drug interactions.