Cenforce LD combines Sildenafil citrate and Dapoxetine to treat both erectile dysfunction (ED) and premature ejaculation (PE). While effective for these conditions, cardiovascular safety is an important consideration, especially since both ED and heart health are closely linked. Sildenafil works by relaxing blood vessels, which lowers blood pressure. This can be risky for men with certain heart conditions, such as unstable angina, recent heart attacks, severe heart failure, or uncontrolled hypertension. Using Sildenafil with nitrate medications (commonly prescribed for chest pain) can cause dangerous drops in blood pressure, leading to fainting or even heart attacks.